2024 AND BEFORE

Selected publications

	1. Pervasive Transcriptome Interactions of Protein-Targeted Drugs Fang L, Velema WA, Lee Y, Xiao L, Mohsen MG, Kietrys AM, Kool ET Nature Chemistry, 2023, 15, 1374-1383 [Full text] [PDF] [Code] [bioRxiv 2022]
	2. Reversible 2´-OH Acylation Enhances RNA stability Fang L, Xiao L, Jun YW, Onishi Y, Kool ET Nature Chemistry, 2023, 15, 1296-1305 [Full text] [PDF]
	3. Reactivity-Based RNA Profiling for Analyzing Transcriptome Interactions of Small Molecules in Human Cells Fang L, Kool ET STAR Protocols, 2023, 4, 102670 [Full text] [PDF]
	4. Chemoproteomic Method for Profiling Inhibitor-Bound Kinase Complexes Fang L, Chakraborty S, Dieter EM, Potter ZE, Lombard CK, Maly DJ Journal of American Chemical Society, 2019, 141, 30, 11912-11922 [Full text] [PDF]
	5.How ATP-Competitive Inhibitors Allosterically Modulate Tyrosine Kinases That Contain a Src-like Regulatory Architecture Fang L, Vilas-Boas J, Chakraborty S, Potter ZE, Register AC, Seeliger MA, Maly DJ ACS Chemical Biology, 2020, 15, 7, 2005-2016 [Full text] [PDF]

Full list (2024 and before):

14. Fang L, Velema WA, Lee Y, Xiao L, Mohsen MG, Kietrys AM, Kool ET, Pervasive Transcriptome Interactions of Protein-Targeted Drugs, Nat. Chem., 2023, 15, 1374-1383. [PDF]

13. Fang L, Xiao L, Jun YW, Onishi Y, Kool ET, Reversible 2´-OH Acylation Enhances RNA stability, Nat. Chem., 2023, 15, 1296-1305. [PDF]

12. Fang L, Kool ET, Reactivity-Based RNA Profiling for Analyzing Transcriptome Interactions of Small Molecules in Human Cells, STAR Protocols, 2023, 4, 102670 [PDF]

11. Fang L, Chakraborty S, Dieter EM, Potter ZE, Lombard CK, Maly DJ, Chemoproteomic Method for Profiling Inhibitor-Bound Kinase Complexes, J. Am. Chem. Soc., 2019, 141, 30, 11912-11922. [PDF]

10. Fang L, Vilas-Boas J, Chakraborty S, Potter ZE, Register AC, Seeliger MA, Maly DJ, How ATP-Competitive Inhibitors Allosterically Modulate Tyrosine Kinases That Contain a Src-like Regulatory Architecture, ACS Chem. Biol., 2020, 15, 7, 2005-2016. [PDF]

9.   Xiao L, Fang L, Kool ET, 2´-OH as a Universal Handle for Studying Intracellular RNAs, Cell Chem. Biol., 2023, 31, 110-124. Review article. [PDF]

8.  Xiao L, Fang L, Chatterjee S, Kool ET, Diverse Reagent Scaffolds Provide Differential Selectivity of 2´-OH Acylation in RNA, J. Am. Chem. Soc., 2023, 145, 143-151. [PDF]

7.   #Chakraborty S, #Ahler E, Simon JJ, Fang L, Potter ZE, Sitko KA, Stephany JJ, Guttman M, Fowler DM, Maly DJ, Profiling of the drug resistance of thousands of Src tyrosine kinase mutants uncovers a regulatory network that couples autoinhibition to the dynamics of the catalytic domain, Cell Chem. Biol., 2023, 23, 2451-9456. [PDF]

6.   Xiao L, Fang L, Kool ET, Acylation Probing of ‘Generic’ RNA Libraries Reveals Critical Influence of Loop Constraints on Reactivity, Cell Chem. Biol., 2022, 29, 1–12. [PDF] 

5.   Fang L, Maly DJ, Finding the Right Key to the Lock: A Chemical and Genetic Toolkit for Interrogating DCLK1, Cell Chem. Biol., 2020, 27, 10, 1221-1223. Preview article. [PDF]

4.   Potter ZE, Lau H, Chakraborty S, Fang L, Guttman M, Ong S, Fowler DM, Maly DJ, Parallel Chemoselective Profiling for Mapping Protein Structure, Cell Chem. Biol., 2020, 27, 8, 1084-1096. [PDF]

3.   Chakraborty S, Inukai T, Fang L, Golkowski M, Maly DJ, Targeting Dynamic ATP-Binding Site Features Allows Discrimination Between Highly Homologous Protein Kinases, ACS Chem. Biol., 2019, 14, 6, 1249-1259. [PDF]

2.   #Ahler E, #Register AC, Chakraborty S, Fang L, Dieter EM, Sitko KA, Vidadala R, Trevillian BM, Golkowski M, Gelman H, Stephany JJ, Rubin AF, Merritt EA, Fowler DM, Maly DJ, A Combined Approach Reveals a Regulatory Mechanism Coupling Src’s Kinase Activity, Localization, and Phosphotransferase-Independent Functions, Molecular Cell, 2019, 74, 393-408. [PDF]

1.  Li S, Fang L, Zhong J, Shen J, Xu H, Yang Y, Hou S, Bian Q, Catalytic Asymmetric Synthesis of the Colorado Potato Beetle Pheromone and Its Enantiomer, Tetrahedron: Asymmetry, 2014, 25, 591-595. [PDF]